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CREON Complete patient resources

It’s important for patients to start and stay on track with the treatment you’ve prescribed

You can find useful information and resources to share with them, below.


Help your CREON patients enroll in CREON Complete.

Insurance 101

Help your patients understand the ins and outs of insurance coverage and costs.

Download the brochure

1:1 support

1:1 CREON support means your patients will have a dedicated Ambassador to help them along the treatment path you’ve prescribed.

Explore the program

Dosing guide

Determine an appropriate per-meal dose or dosing range for each patient.

Use dosing guide

CREON Treatment Tracker

The treatment and diet tracker will help your patients track what they eat and how it affects them.

Download the tracker

CREON educational videos

Watch real gastroenterologists and patients share insights about CREON and living with exocrine pancreatic insufficiency (EPI).

Watch videos now

Contact a representative

Request information about EPI and CREON, patient starter kits, product samples, resource materials, and more.

Contact a rep

CREON Complete may help your patients every step of the way

The program offers eligible patients potential ways to save on their medication, dedicated 1:1 CREON support, educational resources, and more.

Indications and Important Safety


CREON® (pancrelipase) delayed-release capsules are indicated for the treatment of exocrine pancreatic insufficiency in adult and pediatric patients.

Important Safety Information

  • Fibrosing colonopathy has been reported following treatment with pancreatic enzyme products. Do not exceed the recommended dosage of 2,500 lipase units/kg/meal (or 10,000 lipase units/kg/day) or 4,000 lipase units/g fat ingested/day in adult and pediatric patients greater than 12 months of age without further investigation.
  • To avoid irritation of oral mucosa, care should be taken to ensure that CREON is not crushed, chewed, or retained in the mouth. CREON should always be taken with food.
  • Pancreatic enzyme products contain purines that may increase blood uric acid levels. High dosages have been associated with hyperuricosuria and hyperuricemia. Consider monitoring blood uric acid levels in patients with gout, renal impairment, or hyperuricemia during treatment with CREON.
  • There is theoretical risk of viral transmission with all pancreatic enzyme products including CREON.
  • Severe hypersensitivity reactions including anaphylaxis, asthma, hives, and pruritus have been reported with pancreatic enzyme products. Monitor patients with a known hypersensitivity reaction to proteins of porcine origin for hypersensitivity reactions during treatment with CREON.
  • Adverse reactions that occurred in at least 2 cystic fibrosis patients (greater than or equal to 4%) receiving CREON were vomiting, dizziness, and cough.
  • Adverse reactions that occurred in at least 1 chronic pancreatitis or pancreatectomy patient (greater than or equal to 4%) receiving CREON were hyperglycemia, hypoglycemia, abdominal pain, abnormal feces, flatulence, frequent bowel movements, and nasopharyngitis.

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.